The girls regional round kicked off Tuesday at neutral sites across the state. Powerhouse Goodrich met Frankenmuth at Carrollton.
Frankenmuth scored the first two points of the game, but the Goodrich went on a 19-0 run thanks in part to Tania Davis's pair of three pointers.
Davis ended the night with 14 points, as Goodrich wins it 66-25.
Arthur Hill beat Clarkston 54-46.
Midland beat Davison 50-44, so Arthur Hill and Midland will meet Thursday in the regional final.
Valley Lutheran rolled passed Marlette 75-48, they will play Nouvel on Thursday.
Hamady fell to Grosse Pointe Woods University Leggit 51-33.